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The 15 All-Time Best-Selling Prescription Drugs

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Most people may not know it, but only a handful out of every thousand drugs that begin development ever make it to the final stages of trials – and not all of those are approved.

Still, the low odds of success are worth it to drug companies. See, what many people may not fully appreciate is how much revenue one of these approved drugs can rack up in just a few years. A so-called “blockbuster” drug can be worth at least a billion dollars. In some cases, treatments can be worth tens of billions. And in a couple cases, drugs have produced more than $100 billion in revenues over their extremely useful lives.


With that as the backdrop, here’s a rundown of the drug market’s 15 most successful drugs in terms of revenue. Some of them still are in their prime and driving strong revenues for their creators, while others are not. But all of these drugs have been game changers for their respective companies, and shaped the lives of millions of people.

SEE ALSO: 50 Ways to Cut Your Health Care Costs

Data is as of Nov. 30, 2017. Click on ticker-symbol links in each slide for current share prices and more.


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